TY - GEN AB - Optical absorption spectroscopy of individual tissue components is commonly used to identify optimum wavelengths for noninvasive light-based physiological monitoring. However, absorption spectroscopy has historically covered primarily the VIS and NIR wavelengths ranging from 400 to 1,000 nm. This limitation was primarily due to hardware lacking sensitivity at longer wavelengths. Hardware advancements in the SWIR range have enabled investigators to explore the SWIR wavelength range, from approximately 1,000 nm up to 3,000 nm. This region has characteristic absorption peaks for lipid, protein, and water, which are difficult to visualize in the VIS-NIR and can provide label-free sources of biological contrast. Additionally, melanin, the primary chromophore responsible for skin pigmentation, has lower SWIR absorption. Researchers have found that in vivo optical devices like clinically standard pulse oximeters may have reduced accuracy in people with darkly pigmented skin because they do not account for stronger melanin absorption in the VIS and NIR range. Thus, devices operating in the SWIR could significantly reduce error due to skin pigmentation. Understanding the absorption properties of core tissue components from the VIS to the SWIR range is vital for effective optical instrument design. These datasets provide detailed absorption values spanning the VIS to the SWIR of the following common tissue absorbers: oxygenated hemoglobin, deoxygenated hemoglobin, melanin, water, and lipids. AD - Washington University in St. Louis AD - Washington University in St. Louis AD - Washington University in St. Louis AD - Washington University in St. Louis AD - Washington University in St. Louis AD - Washington University in St. Louis AU - O'Brien, Christine AU - Gruensfelder, Hannah AU - Shofu, Folaoluwashewa AU - Michie, Megan AU - Berezin, Mikhail AU - Shmuylovich, Leonid DA - 2024-10-17 DO - 10.7936/6rxs-108249 DO - doi ED - Gruensfelder, Hannah ED - ProjectLeader ID - 108249 KW - Biological sciences KW - Medical engineering KW - Health sciences KW - Absorption Spectroscopy KW - Short-Wave Infrared (SWIR) KW - Visible KW - Hemoglobin KW - Deoxygenated Hemoglobin KW - Water KW - Corn Oil KW - Melanin L1 - https://data.library.wustl.edu/record/108249/files/Corn_Oil_Absorbance_Values.xlsx L1 - https://data.library.wustl.edu/record/108249/files/Deoxygenated_Hemoglobin_Absorbance_Values.xlsx L1 - https://data.library.wustl.edu/record/108249/files/Deuterated_Water_Absorbance_Values.xlsx L1 - https://data.library.wustl.edu/record/108249/files/Melanin_Absorbance_Values.xlsx L1 - https://data.library.wustl.edu/record/108249/files/MilliQ_Water_Absorbance_Values.xlsx L1 - https://data.library.wustl.edu/record/108249/files/Oxygenated_Hemoglobin_Absorbance_Values.xlsx L1 - https://data.library.wustl.edu/record/108249/files/readme_doi1079366rxs108249_gruensfelder.txt L1 - https://data.library.wustl.edu/record/108249/files/Corn_Oil_Absorbance_Values.csv L1 - https://data.library.wustl.edu/record/108249/files/Deoxygenated_Hemoglobin_Absorbance_Values.csv L1 - https://data.library.wustl.edu/record/108249/files/Deuterated_Water_Absorbance_Values.csv L1 - https://data.library.wustl.edu/record/108249/files/Melanin_Absorbance_Values.csv L1 - https://data.library.wustl.edu/record/108249/files/MilliQ_Water_Absorbance_Values.csv L1 - https://data.library.wustl.edu/record/108249/files/Oxygenated_Hemoglobin_Absorbance_Values.csv L2 - https://data.library.wustl.edu/record/108249/files/Corn_Oil_Absorbance_Values.xlsx L2 - https://data.library.wustl.edu/record/108249/files/Deoxygenated_Hemoglobin_Absorbance_Values.xlsx L2 - https://data.library.wustl.edu/record/108249/files/Deuterated_Water_Absorbance_Values.xlsx L2 - https://data.library.wustl.edu/record/108249/files/Melanin_Absorbance_Values.xlsx L2 - https://data.library.wustl.edu/record/108249/files/MilliQ_Water_Absorbance_Values.xlsx L2 - https://data.library.wustl.edu/record/108249/files/Oxygenated_Hemoglobin_Absorbance_Values.xlsx L2 - https://data.library.wustl.edu/record/108249/files/readme_doi1079366rxs108249_gruensfelder.txt L2 - https://data.library.wustl.edu/record/108249/files/Corn_Oil_Absorbance_Values.csv L2 - https://data.library.wustl.edu/record/108249/files/Deoxygenated_Hemoglobin_Absorbance_Values.csv L2 - https://data.library.wustl.edu/record/108249/files/Deuterated_Water_Absorbance_Values.csv L2 - https://data.library.wustl.edu/record/108249/files/Melanin_Absorbance_Values.csv L2 - https://data.library.wustl.edu/record/108249/files/MilliQ_Water_Absorbance_Values.csv L2 - https://data.library.wustl.edu/record/108249/files/Oxygenated_Hemoglobin_Absorbance_Values.csv L4 - https://data.library.wustl.edu/record/108249/files/Corn_Oil_Absorbance_Values.xlsx L4 - https://data.library.wustl.edu/record/108249/files/Deoxygenated_Hemoglobin_Absorbance_Values.xlsx L4 - https://data.library.wustl.edu/record/108249/files/Deuterated_Water_Absorbance_Values.xlsx L4 - https://data.library.wustl.edu/record/108249/files/Melanin_Absorbance_Values.xlsx L4 - https://data.library.wustl.edu/record/108249/files/MilliQ_Water_Absorbance_Values.xlsx L4 - https://data.library.wustl.edu/record/108249/files/Oxygenated_Hemoglobin_Absorbance_Values.xlsx L4 - https://data.library.wustl.edu/record/108249/files/readme_doi1079366rxs108249_gruensfelder.txt L4 - https://data.library.wustl.edu/record/108249/files/Corn_Oil_Absorbance_Values.csv L4 - https://data.library.wustl.edu/record/108249/files/Deoxygenated_Hemoglobin_Absorbance_Values.csv L4 - https://data.library.wustl.edu/record/108249/files/Deuterated_Water_Absorbance_Values.csv L4 - https://data.library.wustl.edu/record/108249/files/Melanin_Absorbance_Values.csv L4 - https://data.library.wustl.edu/record/108249/files/MilliQ_Water_Absorbance_Values.csv L4 - https://data.library.wustl.edu/record/108249/files/Oxygenated_Hemoglobin_Absorbance_Values.csv LA - eng LK - https://data.library.wustl.edu/record/108249/files/Corn_Oil_Absorbance_Values.xlsx LK - https://data.library.wustl.edu/record/108249/files/Deoxygenated_Hemoglobin_Absorbance_Values.xlsx LK - https://data.library.wustl.edu/record/108249/files/Deuterated_Water_Absorbance_Values.xlsx LK - https://data.library.wustl.edu/record/108249/files/Melanin_Absorbance_Values.xlsx LK - https://data.library.wustl.edu/record/108249/files/MilliQ_Water_Absorbance_Values.xlsx LK - https://data.library.wustl.edu/record/108249/files/Oxygenated_Hemoglobin_Absorbance_Values.xlsx LK - https://data.library.wustl.edu/record/108249/files/readme_doi1079366rxs108249_gruensfelder.txt LK - https://data.library.wustl.edu/record/108249/files/Corn_Oil_Absorbance_Values.csv LK - https://data.library.wustl.edu/record/108249/files/Deoxygenated_Hemoglobin_Absorbance_Values.csv LK - https://data.library.wustl.edu/record/108249/files/Deuterated_Water_Absorbance_Values.csv LK - https://data.library.wustl.edu/record/108249/files/Melanin_Absorbance_Values.csv LK - https://data.library.wustl.edu/record/108249/files/MilliQ_Water_Absorbance_Values.csv LK - https://data.library.wustl.edu/record/108249/files/Oxygenated_Hemoglobin_Absorbance_Values.csv N2 - Optical absorption spectroscopy of individual tissue components is commonly used to identify optimum wavelengths for noninvasive light-based physiological monitoring. However, absorption spectroscopy has historically covered primarily the VIS and NIR wavelengths ranging from 400 to 1,000 nm. This limitation was primarily due to hardware lacking sensitivity at longer wavelengths. Hardware advancements in the SWIR range have enabled investigators to explore the SWIR wavelength range, from approximately 1,000 nm up to 3,000 nm. This region has characteristic absorption peaks for lipid, protein, and water, which are difficult to visualize in the VIS-NIR and can provide label-free sources of biological contrast. Additionally, melanin, the primary chromophore responsible for skin pigmentation, has lower SWIR absorption. Researchers have found that in vivo optical devices like clinically standard pulse oximeters may have reduced accuracy in people with darkly pigmented skin because they do not account for stronger melanin absorption in the VIS and NIR range. Thus, devices operating in the SWIR could significantly reduce error due to skin pigmentation. Understanding the absorption properties of core tissue components from the VIS to the SWIR range is vital for effective optical instrument design. These datasets provide detailed absorption values spanning the VIS to the SWIR of the following common tissue absorbers: oxygenated hemoglobin, deoxygenated hemoglobin, melanin, water, and lipids. PB - Washington University in St. Louis PY - 2024-10-17 T1 - Optical Absorption Spectroscopy Values of Common Biological Absorbers Spanning the Visible to the Short-Wave Infrared [dataset] TI - Optical Absorption Spectroscopy Values of Common Biological Absorbers Spanning the Visible to the Short-Wave Infrared [dataset] UR - https://data.library.wustl.edu/record/108249/files/Corn_Oil_Absorbance_Values.xlsx UR - https://data.library.wustl.edu/record/108249/files/Deoxygenated_Hemoglobin_Absorbance_Values.xlsx UR - https://data.library.wustl.edu/record/108249/files/Deuterated_Water_Absorbance_Values.xlsx UR - https://data.library.wustl.edu/record/108249/files/Melanin_Absorbance_Values.xlsx UR - https://data.library.wustl.edu/record/108249/files/MilliQ_Water_Absorbance_Values.xlsx UR - https://data.library.wustl.edu/record/108249/files/Oxygenated_Hemoglobin_Absorbance_Values.xlsx UR - https://data.library.wustl.edu/record/108249/files/readme_doi1079366rxs108249_gruensfelder.txt UR - https://data.library.wustl.edu/record/108249/files/Corn_Oil_Absorbance_Values.csv UR - https://data.library.wustl.edu/record/108249/files/Deoxygenated_Hemoglobin_Absorbance_Values.csv UR - https://data.library.wustl.edu/record/108249/files/Deuterated_Water_Absorbance_Values.csv UR - https://data.library.wustl.edu/record/108249/files/Melanin_Absorbance_Values.csv UR - https://data.library.wustl.edu/record/108249/files/MilliQ_Water_Absorbance_Values.csv UR - https://data.library.wustl.edu/record/108249/files/Oxygenated_Hemoglobin_Absorbance_Values.csv Y1 - 2024-10-17 ER -